Induction of dopamine biosynthesis by l-DOPA in PC12 cells: implications of L-DOPA influx and cyclic AMP.

Jin, Chun Mei; Yang, Yoo Jung; Huang, Hai Shan; Lim, Sung Cil; Kai, Masaaki; Lee, Myung Koo

Jin, Chun Mei; Yang, Yoo Jung; Huang, Hai Shan; Lim, Sung Cil; Kai, Masaaki; Lee, Myung Koo.

Affiliation

Jin CM; College of Pharmacy and Research Center for Bioresource and Health, Chungbuk National University, Cheongju 361-763, Republic of Korea.

Eur J Pharmacol ; 591(1-3): 88-95, 2008 Sep 04.

Article in En | MEDLINE | ID: mdl-18602388

Subject(s)

Cyclic AMP/metabolism; Dopamine/biosynthesis; Levodopa/pharmacology; Receptors, Dopamine D1/drug effects; Animals; Aromatic-L-Amino-Acid Decarboxylases/drug effects; Aromatic-L-Amino-Acid Decarboxylases/metabolism; Cyclic AMP-Dependent Protein Kinases/drug effects; Cyclic AMP-Dependent Protein Kinases/metabolism; Decarboxylation/drug effects; Dose-Response Relationship, Drug; Levodopa/administration & dosage; PC12 Cells; Rats; Receptors, Dopamine D1/metabolism; Signal Transduction/drug effects; Time Factors; Tyrosine 3-Monooxygenase/drug effects; Tyrosine 3-Monooxygenase/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dopamine / Levodopa / Receptors, Dopamine D1 / Cyclic AMP Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2008 Document type: Article

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