Gemcitabine uptake in glioblastoma multiforme: potential as a radiosensitizer.

Sigmond, J; Honeywell, R J; Postma, T J; Dirven, C M F; de Lange, S M; van der Born, K; Laan, A C; Baayen, J C A; Van Groeningen, C J; Bergman, A M; Giaccone, G; Peters, G J

Sigmond, J; Honeywell, R J; Postma, T J; Dirven, C M F; de Lange, S M; van der Born, K; Laan, A C; Baayen, J C A; Van Groeningen, C J; Bergman, A M; Giaccone, G; Peters, G J.

Affiliation

Sigmond J; Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands.

Ann Oncol ; 20(1): 182-7, 2009 Jan.

Article in En | MEDLINE | ID: mdl-18701427

Subject(s)

Brain Neoplasms/metabolism; Deoxycytidine/analogs & derivatives; Glioblastoma/metabolism; Radiation-Sensitizing Agents/pharmacokinetics; Adult; Aged; Antimetabolites, Antineoplastic/blood; Antimetabolites, Antineoplastic/pharmacokinetics; Antimetabolites, Antineoplastic/therapeutic use; Biological Availability; Biopsy; Brain Neoplasms/drug therapy; Brain Neoplasms/pathology; Brain Neoplasms/surgery; Cytidine Deaminase; Deoxycytidine/blood; Deoxycytidine/pharmacokinetics; Deoxycytidine/therapeutic use; Deoxycytidine Kinase/metabolism; Female; Floxuridine/blood; Floxuridine/pharmacokinetics; Floxuridine/therapeutic use; Glioblastoma/drug therapy; Glioblastoma/pathology; Glioblastoma/surgery; Humans; Male; Middle Aged; Nucleoside Deaminases/metabolism; Radiation-Sensitizing Agents/therapeutic use; Gemcitabine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation-Sensitizing Agents / Brain Neoplasms / Glioblastoma / Deoxycytidine Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Ann Oncol Year: 2009 Document type: Article

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