A comparative autoradiography study in post mortem whole hemisphere human brain slices taken from Alzheimer patients and age-matched controls using two radiolabelled DAA1106 analogues with high affinity to the peripheral benzodiazepine receptor (PBR) system.

Gulyás, Balázs; Makkai, Boglárka; Kása, Péter; Gulya, Károly; Bakota, Lidia; Várszegi, Szilvia; Beliczai, Zsuzsa; Andersson, Jan; Csiba, László; Thiele, Andrea; Dyrks, Thomas; Suhara, Tetsua; Suzuki, Kazutoshi; Higuchi, Makato; Halldin, Christer

Gulyás, Balázs; Makkai, Boglárka; Kása, Péter; Gulya, Károly; Bakota, Lidia; Várszegi, Szilvia; Beliczai, Zsuzsa; Andersson, Jan; Csiba, László; Thiele, Andrea; Dyrks, Thomas; Suhara, Tetsua; Suzuki, Kazutoshi; Higuchi, Makato; Halldin, Christer.

Affiliation

Gulyás B; Karolinska Institutet, Department of Clinical Neurosciences, Psychiatry Section, S-171 76 Stockholm, Sweden. balazs.gulyas@ki.se

Neurochem Int ; 54(1): 28-36, 2009 Jan.

Article in En | MEDLINE | ID: mdl-18984021

Subject(s)

Alzheimer Disease/metabolism; Brain/metabolism; Receptors, GABA-A/metabolism; Acetamides/metabolism; Aged, 80 and over; Autoradiography; Female; Humans; Immunohistochemistry; Iodine Radioisotopes; Kinetics; Male; Middle Aged; Phenyl Ethers/metabolism; Postmortem Changes; Reference Values

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Brain / Receptors, GABA-A / Alzheimer Disease Limits: Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Neurochem Int Year: 2009 Document type: Article

Fulltext

XML

PubMed Links

Search on Google