Progression of dopaminergic dysfunction in a LRRK2 kindred: a multitracer PET study.

Nandhagopal, R; Mak, E; Schulzer, M; McKenzie, J; McCormick, S; Sossi, V; Ruth, T J; Strongosky, A; Farrer, M J; Wszolek, Z K; Stoessl, A J

Nandhagopal, R; Mak, E; Schulzer, M; McKenzie, J; McCormick, S; Sossi, V; Ruth, T J; Strongosky, A; Farrer, M J; Wszolek, Z K; Stoessl, A J.

Affiliation

Nandhagopal R; Pacific Parkinson's Research Centre, Vancouver, BC, Canada V6T2B5.

Neurology ; 71(22): 1790-5, 2008 Nov 25.

Article in En | MEDLINE | ID: mdl-19029519

Subject(s)

Dopamine/metabolism; Parkinson Disease/diagnostic imaging; Parkinson Disease/genetics; Positron-Emission Tomography; Protein Serine-Threonine Kinases/genetics; Adult; Aged; Disease Progression; Dopamine Plasma Membrane Transport Proteins/metabolism; Female; Follow-Up Studies; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Linear Models; Male; Middle Aged; Parkinson Disease/metabolism; Positron-Emission Tomography/methods; Predictive Value of Tests; Putamen/metabolism; Radiopharmaceuticals

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Dopamine / Protein Serine-Threonine Kinases / Positron-Emission Tomography Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Neurology Year: 2008 Document type: Article

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