Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion.

Michael, Lowell Evan; Westerman, Bart A; Ermilov, Alexandre N; Wang, Aiqin; Ferris, Jennifer; Liu, Jianhong; Blom, Marleen; Ellison, David W; van Lohuizen, Maarten; Dlugosz, Andrzej A

Michael, Lowell Evan; Westerman, Bart A; Ermilov, Alexandre N; Wang, Aiqin; Ferris, Jennifer; Liu, Jianhong; Blom, Marleen; Ellison, David W; van Lohuizen, Maarten; Dlugosz, Andrzej A.

Affiliation

Michael LE; Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 48109-0932, USA.

Neoplasia ; 10(12): 1343-9, 5p following 1349, 2008 Dec.

Article in En | MEDLINE | ID: mdl-19048113

Subject(s)

Gene Expression Regulation, Neoplastic; Hedgehog Proteins/metabolism; Medulloblastoma/metabolism; Nuclear Proteins/physiology; Proto-Oncogene Proteins/physiology; Repressor Proteins/physiology; Animals; Brain Neoplasms/metabolism; Cell Proliferation; Cerebellum/metabolism; Cyclin D1/metabolism; Cyclin-Dependent Kinase Inhibitor p16/metabolism; Genotype; Glial Fibrillary Acidic Protein; Mice; Mice, Transgenic; Nerve Tissue Proteins/metabolism; Nuclear Proteins/metabolism; Polycomb Repressive Complex 1; Promoter Regions, Genetic; Proto-Oncogene Proteins/metabolism; Repressor Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Nuclear Proteins / Gene Expression Regulation, Neoplastic / Proto-Oncogene Proteins / Hedgehog Proteins / Medulloblastoma Limits: Animals Language: En Journal: Neoplasia Year: 2008 Document type: Article

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