Isoproterenol-induced heart failure in the rat is associated with nitric oxide-dependent functional alterations of cardiac function.

Krenek, Peter; Kmecova, Jana; Kucerova, Dana; Bajuszova, Zuzana; Musil, Peter; Gazova, Andrea; Ochodnicky, Peter; Klimas, Jan; Kyselovic, Jan

Krenek, Peter; Kmecova, Jana; Kucerova, Dana; Bajuszova, Zuzana; Musil, Peter; Gazova, Andrea; Ochodnicky, Peter; Klimas, Jan; Kyselovic, Jan.

Affiliation

Krenek P; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University, Odbojárov 10, 832 32 Bratislava, Slovak Republic. krenek@fpharm.uniba.sk

Eur J Heart Fail ; 11(2): 140-6, 2009 Feb.

Article in En | MEDLINE | ID: mdl-19168511

Subject(s)

Heart Failure/physiopathology; Heart Rate; Isoproterenol; Myocardial Contraction; Nitric Oxide/physiology; Adrenergic beta-Agonists/pharmacology; Animals; Cardiac Pacing, Artificial; Electrocardiography; Enzyme Inhibitors/pharmacology; Heart Atria/physiopathology; Heart Failure/chemically induced; Heart Rate/drug effects; Heart Ventricles/metabolism; In Vitro Techniques; Isoproterenol/pharmacology; Male; Myocardial Contraction/drug effects; NG-Nitroarginine Methyl Ester/pharmacology; Nitric Oxide/antagonists & inhibitors; Nitric Oxide Synthase/metabolism; Rats; Rats, Wistar

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heart Failure / Heart Rate / Isoproterenol / Myocardial Contraction / Nitric Oxide Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Eur J Heart Fail Year: 2009 Document type: Article

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