Vasoformative disorder, resembling littoral cell angioma, of the spleen in a geriatric Japanese macaque (Macaca fuscata).
Vet Pathol
; 46(3): 520-5, 2009 May.
Article
in En
| MEDLINE
| ID: mdl-19176500
ABSTRACT
A 30-year-old female Japanese macaque showed marked splenomegaly. The enlarged spleen consisted of neoplastic proliferation of anastomosing vascular channels resembling morphologic structures of red pulp sinuses; occasionally, papillary fronds were seen in dilated channels. Immunohistochemically, the lining cells reacted to both endothelial cell (von Willebrand factor) and macrophage (macrophage scavenger receptor class A) markers, indicating features of littoral cells of the spleen. Based on the pathologic characteristics, particularly the presence of neoplastic cells with macrophage/histiocyte-like attributes, this tumor was regarded as littoral cell angioma; this is a rare benign splenic vascular tumor.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Splenic Neoplasms
/
Hemangioma
/
Macaca
/
Monkey Diseases
Limits:
Animals
Language:
En
Journal:
Vet Pathol
Year:
2009
Document type:
Article