Heterogeneous in vivo expression of clumping factor A and capsular polysaccharide by Staphylococcus aureus: implications for vaccine design.

Nanra, Jasdeep S; Timofeyeva, Yekaterina; Buitrago, Sandra M; Sellman, Bret R; Dilts, Deborah A; Fink, Pamela; Nunez, Lorna; Hagen, Michael; Matsuka, Yury V; Mininni, Terri; Zhu, Duzhang; Pavliak, Viliam; Green, Bruce A; Jansen, Kathrin U; Anderson, Annaliesa S

Nanra, Jasdeep S; Timofeyeva, Yekaterina; Buitrago, Sandra M; Sellman, Bret R; Dilts, Deborah A; Fink, Pamela; Nunez, Lorna; Hagen, Michael; Matsuka, Yury V; Mininni, Terri; Zhu, Duzhang; Pavliak, Viliam; Green, Bruce A; Jansen, Kathrin U; Anderson, Annaliesa S.

Affiliation

Nanra JS; Wyeth Vaccine Research, 401 N. Middletown Road, Pearl River, NY 10965, USA.

Vaccine ; 27(25-26): 3276-80, 2009 May 26.

Article in En | MEDLINE | ID: mdl-19200819

Subject(s)

Antigens, Bacterial/biosynthesis; Bacterial Capsules/biosynthesis; Coagulase/biosynthesis; Staphylococcal Vaccines/immunology; Staphylococcus aureus/immunology; Animals; Bacteremia/immunology; Bacterial Capsules/analysis; Bacterial Capsules/immunology; Coagulase/analysis; Coagulase/immunology; Drug Design; Female; HL-60 Cells; Humans; Mice; Mice, Inbred C57BL; Phagocytosis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Staphylococcus aureus / Staphylococcal Vaccines / Bacterial Capsules / Coagulase / Antigens, Bacterial Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Vaccine Year: 2009 Document type: Article

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