Predictive diagnosis of the cancer prone Li-Fraumeni syndrome by accident: new challenges through whole genome array testing.

Schwarzbraun, T; Obenauf, A C; Langmann, A; Gruber-Sedlmayr, U; Wagner, K; Speicher, M R; Kroisel, P M

Schwarzbraun, T; Obenauf, A C; Langmann, A; Gruber-Sedlmayr, U; Wagner, K; Speicher, M R; Kroisel, P M.

J Med Genet ; 46(5): 341-4, 2009 May.

Article in En | MEDLINE | ID: mdl-19269943

Subject(s)

Chromosome Deletion; Comparative Genomic Hybridization/methods; Li-Fraumeni Syndrome/genetics; Mutation; Tumor Suppressor Protein p53/genetics; Base Sequence; Child; Chromosome Breakage; Chromosomes, Human, Pair 17/genetics; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Humans; In Situ Hybridization, Fluorescence; Li-Fraumeni Syndrome/complications; Li-Fraumeni Syndrome/diagnosis; Molecular Sequence Data; Neoplasms/etiology; Neoplasms/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Chromosome Deletion / Li-Fraumeni Syndrome / Comparative Genomic Hybridization / Mutation Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Child / Female / Humans Language: En Journal: J Med Genet Year: 2009 Document type: Article

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