Protection by anti-beta-glucan antibodies is associated with restricted beta-1,3 glucan binding specificity and inhibition of fungal growth and adherence.

Torosantucci, Antonella; Chiani, Paola; Bromuro, Carla; De Bernardis, Flavia; Palma, Angelina S; Liu, Yan; Mignogna, Giuseppina; Maras, Bruno; Colone, Marisa; Stringaro, Annarita; Zamboni, Silvia; Feizi, Ten; Cassone, Antonio

Torosantucci, Antonella; Chiani, Paola; Bromuro, Carla; De Bernardis, Flavia; Palma, Angelina S; Liu, Yan; Mignogna, Giuseppina; Maras, Bruno; Colone, Marisa; Stringaro, Annarita; Zamboni, Silvia; Feizi, Ten; Cassone, Antonio.

Affiliation

Torosantucci A; Department of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.

PLoS One ; 4(4): e5392, 2009.

Article in En | MEDLINE | ID: mdl-19399183

Subject(s)

Antibodies, Fungal/administration & dosage; Fungi/immunology; Fungi/pathogenicity; beta-Glucans/antagonists & inhibitors; beta-Glucans/immunology; Amino Acid Sequence; Animals; Antibodies, Fungal/genetics; Antibodies, Monoclonal/administration & dosage; Antibodies, Monoclonal/genetics; Antigens, Fungal/genetics; Base Sequence; Candida albicans/growth & development; Candida albicans/immunology; Candida albicans/pathogenicity; Candida albicans/physiology; Cell Adhesion/immunology; Cell Line; Cell Wall/immunology; DNA, Complementary/genetics; Epitopes/genetics; Female; Fungi/growth & development; Fungi/physiology; Humans; Immunoglobulin G/administration & dosage; Immunoglobulin G/genetics; Immunoglobulin M/administration & dosage; Immunoglobulin M/genetics; Mice; Molecular Sequence Data; Proteoglycans; Rats; Rats, Wistar; beta-Glucans/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Beta-Glucans / Fungi / Antibodies, Fungal Type of study: Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: PLoS One Year: 2009 Document type: Article

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