Doxorubicin-induced platelet cytotoxicity: a new contributory factor for doxorubicin-mediated thrombocytopenia.

Kim, E-J; Lim, K-M; Kim, K-Y; Bae, O-N; Noh, J-Y; Chung, S-M; Shin, S; Yun, Y-P; Chung, J-H

Kim, E-J; Lim, K-M; Kim, K-Y; Bae, O-N; Noh, J-Y; Chung, S-M; Shin, S; Yun, Y-P; Chung, J-H.

Affiliation

Kim EJ; College of Pharmacy, Seoul National University, Seoul, Korea.

J Thromb Haemost ; 7(7): 1172-83, 2009 Jul.

Article in En | MEDLINE | ID: mdl-19426282

Subject(s)

Antineoplastic Agents/pharmacology; Blood Platelets/drug effects; Doxorubicin/pharmacology; Thrombocytopenia/chemically induced; Adolescent; Adult; Antineoplastic Agents/adverse effects; Blood Platelets/enzymology; Blood Platelets/metabolism; Caspase 3/metabolism; Doxorubicin/adverse effects; Flow Cytometry; Humans; Male; Reactive Oxygen Species/metabolism; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombocytopenia / Blood Platelets / Doxorubicin / Antineoplastic Agents Type of study: Prognostic_studies Limits: Adolescent / Adult / Humans / Male Language: En Journal: J Thromb Haemost Year: 2009 Document type: Article

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