Labeling patterned DNA molecules using CdS fluorescence nanoparticles.

ABSTRACT

We present the detection of patterned DNA molecules fixed on quartz substrates using CdS florescence quantum dots, and the linear assembly of CdS nanoparticles based on DNA templates. The detection and the assembling processes were recognized by the bright spots arraying in grid patterns resulting from the fluorescence of CdS nanoparticles by means of dark optical microscopy, which attribute to the complementation process of DNA molecules and the electrostatic interaction between the DNA with positive charges and CdS nanocrystals with negative charges. In addition, the photoluminescence (PL) emission characteristics of temperature dependence and decay of DNA-CdS samples are analyzed.