A novel technique for selective NF-kappaB inhibition in Kupffer cells: contrary effects in fulminant hepatitis and ischaemia-reperfusion.

Hoffmann, F; Sass, G; Zillies, J; Zahler, S; Tiegs, G; Hartkorn, A; Fuchs, S; Wagner, J; Winter, G; Coester, C; Gerbes, A L; Vollmar, A M

Hoffmann, F; Sass, G; Zillies, J; Zahler, S; Tiegs, G; Hartkorn, A; Fuchs, S; Wagner, J; Winter, G; Coester, C; Gerbes, A L; Vollmar, A M.

Affiliation

Hoffmann F; Department of Pharmacy, Center of Drug Research, Butenandtstrasse 5-13, D-81377 Munich, Germany.

Gut ; 58(12): 1670-8, 2009 Dec.

Article in En | MEDLINE | ID: mdl-19470497

Subject(s)

Kupffer Cells/metabolism; Liver Failure, Acute/prevention & control; NF-kappa B/antagonists & inhibitors; Oligodeoxyribonucleotides/therapeutic use; Reperfusion Injury/prevention & control; Animals; Apoptosis; Disease Models, Animal; Gelatin/metabolism; Genetic Therapy/methods; Liver/blood supply; Liver Failure, Acute/metabolism; Liver Failure, Acute/pathology; Male; Mice; NF-kappa B/metabolism; Nanoparticles; Oligodeoxyribonucleotides/pharmacokinetics; Rats; Rats, Sprague-Dawley; Reperfusion Injury/metabolism; Reperfusion Injury/pathology; Signal Transduction; Translocation, Genetic

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Health context: 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Oligodeoxyribonucleotides / Reperfusion Injury / NF-kappa B / Liver Failure, Acute / Kupffer Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: Gut Year: 2009 Document type: Article

Fulltext

XML

PubMed Links

Search on Google