Regulation of T cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation.

Mukherjee, Sumanta; Schaller, Matthew A; Neupane, Rupak; Kunkel, Steven L; Lukacs, Nicholas W

Mukherjee, Sumanta; Schaller, Matthew A; Neupane, Rupak; Kunkel, Steven L; Lukacs, Nicholas W.

Affiliation

Mukherjee S; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

J Immunol ; 182(12): 7381-8, 2009 Jun 15.

Article in En | MEDLINE | ID: mdl-19494260

Subject(s)

Cytokines/immunology; Interleukin-17/biosynthesis; Intracellular Signaling Peptides and Proteins/immunology; Lymphocyte Activation/immunology; Membrane Proteins/immunology; Receptors, Notch/immunology; Receptors, Retinoic Acid/immunology; Receptors, Thyroid Hormone/immunology; T-Lymphocytes/immunology; Adaptor Proteins, Signal Transducing; Animals; Binding Sites; Calcium-Binding Proteins; Cells, Cultured; Interleukin-17/genetics; Interleukin-17/immunology; Mice; Nuclear Receptor Subfamily 1, Group F, Member 3; Promoter Regions, Genetic/genetics; T-Lymphocytes/metabolism; Toll-Like Receptors/immunology; Transcription Factors/immunology; Transcription, Genetic/genetics; Transcription, Genetic/immunology; Up-Regulation/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Thyroid Hormone / Lymphocyte Activation / T-Lymphocytes / Cytokines / Receptors, Retinoic Acid / Interleukin-17 / Intracellular Signaling Peptides and Proteins / Receptors, Notch / Membrane Proteins Limits: Animals Language: En Journal: J Immunol Year: 2009 Document type: Article

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