An improved synthesis of the selective EP4 receptor agonist ONO-4819.

Ohta, Chisa; Kuwabe, Shin-itsu; Shiraishi, Tai; Shinohara, Ikuo; Araki, Hiroshi; Sakuyama, Shigeru; Makihara, Takayuki; Kawanaka, Yasufumi; Ohuchida, Shuichi; Seko, Takuya

Ohta, Chisa; Kuwabe, Shin-itsu; Shiraishi, Tai; Shinohara, Ikuo; Araki, Hiroshi; Sakuyama, Shigeru; Makihara, Takayuki; Kawanaka, Yasufumi; Ohuchida, Shuichi; Seko, Takuya.

Affiliation

Ohta C; Chemical Process Research Laboratories, Fukui Research Institute, Ono Pharmaceutical Co., Ltd., 1-5-2 Technoport, Yamagishi, Mikuni, Sakai, Fukui 913-0032, Japan. ch.ohta@ono.co.jp

J Org Chem ; 74(21): 8298-308, 2009 Nov 06.

Article in En | MEDLINE | ID: mdl-19803523

Subject(s)

Heptanoates/chemical synthesis; Receptors, Prostaglandin E/agonists; Chromatography, High Pressure Liquid; Heptanoates/pharmacology; Magnetic Resonance Spectroscopy; Receptors, Prostaglandin E, EP4 Subtype; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Prostaglandin E / Heptanoates Language: En Journal: J Org Chem Year: 2009 Document type: Article

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