Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.

Xu, Keli; Nieuwenhuis, Erica; Cohen, Brenda L; Wang, Wei; Canty, Angelo J; Danska, Jayne S; Coultas, Leigh; Rossant, Janet; Wu, Megan Y J; Piscione, Tino D; Nagy, Andras; Gossler, Achim; Hicks, Geoff G; Hui, Chi-Chung; Henkelman, R Mark; Yu, Lisa X; Sled, John G; Gridley, Thomas; Egan, Sean E

Xu, Keli; Nieuwenhuis, Erica; Cohen, Brenda L; Wang, Wei; Canty, Angelo J; Danska, Jayne S; Coultas, Leigh; Rossant, Janet; Wu, Megan Y J; Piscione, Tino D; Nagy, Andras; Gossler, Achim; Hicks, Geoff G; Hui, Chi-Chung; Henkelman, R Mark; Yu, Lisa X; Sled, John G; Gridley, Thomas; Egan, Sean E.

Affiliation

Xu K; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, 101 College St., East Tower, Rm. 14-309, Toronto, Ontario, Canada M5G 1L7.

Am J Physiol Lung Cell Mol Physiol ; 298(1): L45-56, 2010 Jan.

Article in En | MEDLINE | ID: mdl-19897741

Subject(s)

Glycosyltransferases/metabolism; Organogenesis; Pulmonary Alveoli/embryology; Receptors, Notch/metabolism; Signal Transduction; Alleles; Animals; Cell Differentiation; Collagen/metabolism; Elastin/metabolism; Fibroblasts/metabolism; Fibroblasts/pathology; Genome/genetics; Immunohistochemistry; Ligands; Mice; Mice, Mutant Strains; Mutation/genetics; Neuroendocrine Cells/metabolism; Neuroendocrine Cells/pathology; Pulmonary Alveoli/abnormalities; Pulmonary Alveoli/pathology; Stem Cells/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Alveoli / Signal Transduction / Glycosyltransferases / Organogenesis / Receptors, Notch Limits: Animals Language: En Journal: Am J Physiol Lung Cell Mol Physiol Year: 2010 Document type: Article

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