Unsaturated and carbocyclic nucleoside analogues: synthesis, antitumor, and antiviral activity.

Phadtare, S; Kessel, D; Corbett, T H; Renis, H E; Court, B A; Zimlicka, J

Phadtare, S; Kessel, D; Corbett, T H; Renis, H E; Court, B A; Zimlicka, J.

Affiliation

Phadtare S; Department of Chemistry, Michigan Cancer Foundation, Detroit 48201.

J Med Chem ; 34(1): 421-9, 1991 Jan.

Article in En | MEDLINE | ID: mdl-1992143

Subject(s)

Antimetabolites, Antineoplastic/chemical synthesis; Antiviral Agents/chemical synthesis; Nucleosides/chemical synthesis; Adenosine Deaminase/metabolism; Animals; Cell Line; Cell Survival/drug effects; Drug Screening Assays, Antitumor; Friend murine leukemia virus/drug effects; HIV-1/drug effects; HIV-2/drug effects; Humans; Indicators and Reagents; Leukemia L1210; Mice; Molecular Structure; Nucleosides/chemistry; Nucleosides/pharmacology; Rauscher Virus/drug effects; Structure-Activity Relationship

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Antimetabolites, Antineoplastic / Nucleosides Limits: Animals / Humans Language: En Journal: J Med Chem Year: 1991 Document type: Article

Search on Google

XML

PubMed Links