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Treg and lupus.
Bonelli, M; Smolen, J S; Scheinecker, C.
Affiliation
  • Bonelli M; Division of Rheumatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Ann Rheum Dis ; 69 Suppl 1: i65-66, 2010 Jan.
Article in En | MEDLINE | ID: mdl-19995748
ABSTRACT
Autoimmune diseases such as systemic lupus erythemathodes (SLE) display quantitative and/or qualitative deficiencies of CD4+CD25+ regulatory T cells (Treg). This might contribute to the immune dysregulation and break-down of peripheral tolerance mechanisms. In addition novel subsets of Treg might arise under specific autoimmune conditions as an effort to counteract autoimmunity. Advances in our understanding of how to characterise and manipulate Treg in patients with autoimmune diseases are required in order to develop new therapeutic strategies.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Regulatory / Lupus Erythematosus, Systemic Type of study: Qualitative_research Limits: Humans Language: En Journal: Ann Rheum Dis Year: 2010 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Regulatory / Lupus Erythematosus, Systemic Type of study: Qualitative_research Limits: Humans Language: En Journal: Ann Rheum Dis Year: 2010 Document type: Article