Treg and lupus.
Ann Rheum Dis
; 69 Suppl 1: i65-66, 2010 Jan.
Article
in En
| MEDLINE
| ID: mdl-19995748
ABSTRACT
Autoimmune diseases such as systemic lupus erythemathodes (SLE) display quantitative and/or qualitative deficiencies of CD4+CD25+ regulatory T cells (Treg). This might contribute to the immune dysregulation and break-down of peripheral tolerance mechanisms. In addition novel subsets of Treg might arise under specific autoimmune conditions as an effort to counteract autoimmunity. Advances in our understanding of how to characterise and manipulate Treg in patients with autoimmune diseases are required in order to develop new therapeutic strategies.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
T-Lymphocytes, Regulatory
/
Lupus Erythematosus, Systemic
Type of study:
Qualitative_research
Limits:
Humans
Language:
En
Journal:
Ann Rheum Dis
Year:
2010
Document type:
Article