Transcripts from a novel BMPR2 termination mutation escape nonsense mediated decay by downstream translation re-initiation: implications for treating pulmonary hypertension.

Hamid, R; Hedges, L K; Austin, E; Phillips, J A; Loyd, J E; Cogan, J D

Hamid, R; Hedges, L K; Austin, E; Phillips, J A; Loyd, J E; Cogan, J D.

Affiliation

Hamid R; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA. rizwan.hamid@vanderbilt.edu

Clin Genet ; 77(3): 280-6, 2010 Mar.

Article in En | MEDLINE | ID: mdl-20095988

Subject(s)

Bone Morphogenetic Protein Receptors, Type II/genetics; Codon, Nonsense; Hypertension, Pulmonary/genetics; Mutation; Aminoglycosides/therapeutic use; Female; Humans; Hypertension, Pulmonary/drug therapy; Lymphocytes; Male; Pedigree

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Codon, Nonsense / Bone Morphogenetic Protein Receptors, Type II / Hypertension, Pulmonary / Mutation Type of study: Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Clin Genet Year: 2010 Document type: Article

Fulltext

XML

PubMed Links

Search on Google