Gene-modified T cells as immunotherapy for multiple myeloma and acute myeloid leukemia expressing the Lewis Y antigen.

Peinert, S; Prince, H M; Guru, P M; Kershaw, M H; Smyth, M J; Trapani, J A; Gambell, P; Harrison, S; Scott, A M; Smyth, F E; Darcy, P K; Tainton, K; Neeson, P; Ritchie, D S; Hönemann, D

Peinert, S; Prince, H M; Guru, P M; Kershaw, M H; Smyth, M J; Trapani, J A; Gambell, P; Harrison, S; Scott, A M; Smyth, F E; Darcy, P K; Tainton, K; Neeson, P; Ritchie, D S; Hönemann, D.

Affiliation

Peinert S; Department of Haematology and Medical Oncology, Peter MacCallum Cancer Centre, Victoria, Australia. stefan.peinert@petermac.org

Gene Ther ; 17(5): 678-86, 2010 May.

Article in En | MEDLINE | ID: mdl-20200563

Subject(s)

Genetic Therapy/methods; Immunotherapy, Adoptive/methods; Leukemia, Myeloid, Acute/therapy; Lewis Blood Group Antigens/immunology; Multiple Myeloma/therapy; Receptors, Antigen, T-Cell/genetics; T-Lymphocytes/transplantation; Animals; Female; Genetic Vectors; Humans; Interferon-gamma/metabolism; Lymphocyte Activation/genetics; Lymphocyte Activation/immunology; Male; Mice; Mice, Inbred NOD; Mice, SCID; Receptors, Antigen, T-Cell/immunology; Retroviridae/genetics; T-Lymphocytes/immunology; Transduction, Genetic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Antigen, T-Cell / T-Lymphocytes / Genetic Therapy / Leukemia, Myeloid, Acute / Immunotherapy, Adoptive / Lewis Blood Group Antigens / Multiple Myeloma Limits: Animals / Female / Humans / Male Language: En Journal: Gene Ther Year: 2010 Document type: Article

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