Preparation and in vitro photodynamic activity of amphiphilic zinc(II) phthalocyanines substituted with 2-(dimethylamino)ethylthio moieties and their N-alkylated derivatives.

Duan, Wubiao; Lo, Pui-Chi; Duan, Lei; Fong, Wing-Ping; Ng, Dennis K P

Duan, Wubiao; Lo, Pui-Chi; Duan, Lei; Fong, Wing-Ping; Ng, Dennis K P.

Affiliation

Duan W; Department of Chemistry and Center of Novel Functional Molecules, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.

Bioorg Med Chem ; 18(7): 2672-7, 2010 Apr 01.

Article in En | MEDLINE | ID: mdl-20223676

Subject(s)

Dimethylamines/chemical synthesis; Dimethylamines/pharmacology; Photosensitizing Agents/chemical synthesis; Photosensitizing Agents/pharmacology; Alkylation; Crystallography, X-Ray; Cyclization; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Photosensitizing Agents/metabolism; Spectrometry, Fluorescence

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Photosensitizing Agents / Dimethylamines Limits: Humans Language: En Journal: Bioorg Med Chem Year: 2010 Document type: Article

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