A concise and convergent synthesis of PA-824.
J Org Chem
; 75(21): 7479-82, 2010 Nov 05.
Article
in En
| MEDLINE
| ID: mdl-20929201
ABSTRACT
An efficient four-step synthesis of PA-824, a promising antituberculosis drug candidate, has been developed. This concise approach offers significant improvements over the synthetic route currently used for large-scale production.
Full text:
1
Collection:
01-internacional
Health context:
3_ND
Database:
MEDLINE
Main subject:
Nitroimidazoles
/
Antitubercular Agents
Language:
En
Journal:
J Org Chem
Year:
2010
Document type:
Article