CXCL4L1 inhibits angiogenesis and induces undirected endothelial cell migration without affecting endothelial cell proliferation and monocyte recruitment.

Sarabi, A; Kramp, B K; Drechsler, M; Hackeng, T M; Soehnlein, O; Weber, C; Koenen, R R; Von Hundelshausen, P

Sarabi, A; Kramp, B K; Drechsler, M; Hackeng, T M; Soehnlein, O; Weber, C; Koenen, R R; Von Hundelshausen, P.

Affiliation

Sarabi A; Institute for Cardiovascular Molecular Research, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.

J Thromb Haemost ; 9(1): 209-19, 2011 Jan.

Article in En | MEDLINE | ID: mdl-20961394

Subject(s)

Angiostatic Proteins/metabolism; Cell Movement; Cell Proliferation; Chemotaxis, Leukocyte; Endothelial Cells/immunology; Inflammation Mediators/metabolism; Monocytes/immunology; Neovascularization, Physiologic; Platelet Factor 4/metabolism; Angiostatic Proteins/chemical synthesis; Angiostatic Proteins/genetics; Animals; Blood Coagulation; Cells, Cultured; Chemokine CCL5/metabolism; Fibroblast Growth Factor 2/metabolism; Humans; Inflammation Mediators/chemical synthesis; Mice; Mice, Inbred C57BL; Partial Thromboplastin Time; Platelet Factor 4/chemical synthesis; Platelet Factor 4/genetics; Protein Multimerization; Recombinant Proteins/metabolism; Time Factors; Vascular Endothelial Growth Factor A/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Platelet Factor 4 / Monocytes / Cell Movement / Chemotaxis, Leukocyte / Inflammation Mediators / Neovascularization, Physiologic / Endothelial Cells / Angiostatic Proteins / Cell Proliferation Limits: Animals / Humans Language: En Journal: J Thromb Haemost Year: 2011 Document type: Article

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