The effect of heparin administration in animal models of sepsis: a prospective study in Escherichia coli-challenged mice and a systematic review and metaregression analysis of published studies.

Li, Yan; Sun, Jun-Feng; Cui, Xizhong; Mani, Haresh; Danner, Robert L; Li, Xuemei; Su, Jun-Wu; Fitz, Yvonne; Eichacker, Peter Q

Li, Yan; Sun, Jun-Feng; Cui, Xizhong; Mani, Haresh; Danner, Robert L; Li, Xuemei; Su, Jun-Wu; Fitz, Yvonne; Eichacker, Peter Q.

Affiliation

Li Y; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA.

Crit Care Med ; 39(5): 1104-12, 2011 May.

Article in En | MEDLINE | ID: mdl-21317646

Subject(s)

Escherichia coli Infections/drug therapy; Escherichia coli; Heparin/administration & dosage; Sepsis/drug therapy; Sepsis/mortality; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Escherichia coli Infections/mortality; Female; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Partial Thromboplastin Time; Random Allocation; Reference Values; Sepsis/microbiology; Survival Rate; Treatment Outcome

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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 / 3_ND Database: MEDLINE Main subject: Heparin / Sepsis / Escherichia coli / Escherichia coli Infections Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Animals Language: En Journal: Crit Care Med Year: 2011 Document type: Article

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