Modern laboratory evaluation of peptide and amines: a continuing role for radioimmunoassay?
Endocrinol Metab Clin North Am
; 40(1): 135-51, viii-ix, 2011 Mar.
Article
in En
| MEDLINE
| ID: mdl-21349415
ABSTRACT
Modern medicine, and specifically clinical diagnosis, relies, among other diagnostic procedures, on the measurements of the biogenic analytes for elucidation and correlation of specific neuroendocrine markers. Tremendous advances have been made in imaging and radioactive uptake procedures to elucidate tumor presence and characterization. However, such advances only partially provide the fundamental degree of tumor activity and clinical confirmational validity. The author points out in some detail the problems that may arise when the methodological differences presented by each investigational study and investigators are not standardized. This variation causes a concern with the specific objectives of the investigator and the specific aims of the research project at hand, and ultimately for the validity of the published results.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Peptides
/
Social Change
/
Clinical Laboratory Techniques
/
Amines
Type of study:
Diagnostic_studies
Aspects:
Determinantes_sociais_saude
Limits:
Humans
Language:
En
Journal:
Endocrinol Metab Clin North Am
Year:
2011
Document type:
Article