Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism.

Kansanen, Emilia; Bonacci, Gustavo; Schopfer, Francisco J; Kuosmanen, Suvi M; Tong, Kit I; Leinonen, Hanna; Woodcock, Steven R; Yamamoto, Masayuki; Carlberg, Carsten; Ylä-Herttuala, Seppo; Freeman, Bruce A; Levonen, Anna-Liisa

Kansanen, Emilia; Bonacci, Gustavo; Schopfer, Francisco J; Kuosmanen, Suvi M; Tong, Kit I; Leinonen, Hanna; Woodcock, Steven R; Yamamoto, Masayuki; Carlberg, Carsten; Ylä-Herttuala, Seppo; Freeman, Bruce A; Levonen, Anna-Liisa.

Affiliation

Kansanen E; Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, FIN-70211 Kuopio, Finland.

J Biol Chem ; 286(16): 14019-27, 2011 Apr 22.

Article in En | MEDLINE | ID: mdl-21357422

Subject(s)

Adaptor Proteins, Signal Transducing/chemistry; Cysteine/chemistry; Cytoskeletal Proteins/chemistry; Fatty Acids/chemistry; Intracellular Signaling Peptides and Proteins/chemistry; NF-E2-Related Factor 2/chemistry; Animals; Chromatography, Liquid/methods; Gene Expression Regulation; Humans; Kelch-Like ECH-Associated Protein 1; Linoleic Acids/chemistry; Mass Spectrometry/methods; Mice; Mutation; Nitro Compounds/chemistry; Oleic Acids/chemistry; Protein Processing, Post-Translational; Signal Transduction; Transcription Factors/metabolism; Ubiquitin-Protein Ligases/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cysteine / Cytoskeletal Proteins / Intracellular Signaling Peptides and Proteins / Adaptor Proteins, Signal Transducing / NF-E2-Related Factor 2 / Fatty Acids Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2011 Document type: Article

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