No extreme genetic risk for type 1 diabetes among DR3/4-DQ8 siblings sharing both extended HLA haplotypes with their diabetic proband.

Eerligh, P; Koeleman, B P C; Lie, B A; Roep, B O; Thorsby, E

Eerligh, P; Koeleman, B P C; Lie, B A; Roep, B O; Thorsby, E.

Affiliation

Eerligh P; Department of Immunohaematology & Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.

Tissue Antigens ; 77(4): 338-40, 2011 Apr.

Article in En | MEDLINE | ID: mdl-21388358

Subject(s)

Alleles; Diabetes Mellitus, Type 1/genetics; HLA-DR3 Antigen/genetics; HLA-DR4 Antigen/genetics; Siblings; Adolescent; Child; Cohort Studies; Female; Genetic Predisposition to Disease; HLA-DQ Antigens; Haplotypes; Humans; Male; Netherlands; Risk Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HLA-DR3 Antigen / HLA-DR4 Antigen / Siblings / Diabetes Mellitus, Type 1 / Alleles Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adolescent / Child / Female / Humans / Male Country/Region as subject: Europa Language: En Journal: Tissue Antigens Year: 2011 Document type: Article

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