Antioxidant dietary supplementation in mice exposed to proton radiation attenuates expression of programmed cell death-associated genes.

Sanzari, J K; Wambi, C; Lewis-Wambi, J S; Kennedy, A R

Sanzari, J K; Wambi, C; Lewis-Wambi, J S; Kennedy, A R.

Affiliation

Sanzari JK; Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

Radiat Res ; 175(5): 650-6, 2011 May.

Article in En | MEDLINE | ID: mdl-21443425

Subject(s)

Antioxidants/pharmacology; Apoptosis/genetics; Dietary Supplements; Gene Expression Regulation/drug effects; Gene Expression Regulation/radiation effects; Protons/adverse effects; Animals; Apoptosis/drug effects; Apoptosis/radiation effects; Bone Marrow Cells/cytology; Bone Marrow Cells/drug effects; Bone Marrow Cells/metabolism; Bone Marrow Cells/radiation effects; Cell Count; Male; Mice; Proto-Oncogene Proteins c-bcl-2/genetics; Proto-Oncogene Proteins c-bcl-2/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Time Factors; Transforming Growth Factor beta1/genetics; Up-Regulation/drug effects; Up-Regulation/radiation effects; Whole-Body Irradiation/adverse effects; bcl-X Protein/genetics; bcl-X Protein/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protons / Gene Expression Regulation / Apoptosis / Dietary Supplements / Antioxidants Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Radiat Res Year: 2011 Document type: Article

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