Dynamics in enzymatic protein complexes offer a novel principle for the regulation of melatonin synthesis in the human pineal gland.

Maronde, Erik; Saade, Anastasia; Ackermann, Katrin; Goubran-Botros, Hany; Pagan, Cecile; Bux, Roman; Bourgeron, Thomas; Dehghani, Faramarz; Stehle, Jörg H

Maronde, Erik; Saade, Anastasia; Ackermann, Katrin; Goubran-Botros, Hany; Pagan, Cecile; Bux, Roman; Bourgeron, Thomas; Dehghani, Faramarz; Stehle, Jörg H.

Affiliation

Maronde E; Institute of Anatomy III, Goethe-University, Frankfurt/Main, Germany.

J Pineal Res ; 51(1): 145-55, 2011 Aug.

Article in En | MEDLINE | ID: mdl-21517958

Subject(s)

Acetylserotonin O-Methyltransferase/metabolism; Arylalkylamine N-Acetyltransferase/metabolism; Melatonin/biosynthesis; Pineal Gland/enzymology; Acetylserotonin O-Methyltransferase/genetics; Acetylserotonin O-Methyltransferase/immunology; Adult; Aged; Analysis of Variance; Animals; Antibodies, Monoclonal/immunology; Antibodies, Monoclonal/pharmacology; Blotting, Western; Female; Humans; Linear Models; Male; Melatonin/metabolism; Microscopy, Fluorescence; Middle Aged; Pineal Gland/metabolism; RNA, Messenger/biosynthesis; RNA, Messenger/genetics; Rats; Sheep

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pineal Gland / Acetylserotonin O-Methyltransferase / Arylalkylamine N-Acetyltransferase / Melatonin Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: J Pineal Res Year: 2011 Document type: Article

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