Oxidative stress and ERK1/2 phosphorylation as predictors of outcome in hepatocellular carcinoma patients treated with sorafenib plus octreotide LAR.

Caraglia, M; Giuberti, G; Marra, M; Addeo, R; Montella, L; Murolo, M; Sperlongano, P; Vincenzi, B; Naviglio, S; Prete, S Del; Abbruzzese, A; Stiuso, P

Caraglia, M; Giuberti, G; Marra, M; Addeo, R; Montella, L; Murolo, M; Sperlongano, P; Vincenzi, B; Naviglio, S; Prete, S Del; Abbruzzese, A; Stiuso, P.

Affiliation

Caraglia M; Department of Biochemistry and Biophysics, Second University of Naples, Naples, Italy. michele.caraglia@unina2.it

Cell Death Dis ; 2: e150, 2011 Apr 28.

Article in En | MEDLINE | ID: mdl-21525937

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Biomarkers, Tumor/blood; Carcinoma, Hepatocellular/drug therapy; Liver Neoplasms/drug therapy; Mitogen-Activated Protein Kinase 1/blood; Mitogen-Activated Protein Kinase 3/blood; Oxidative Stress; Benzenesulfonates/administration & dosage; Carcinoma, Hepatocellular/metabolism; Delayed-Action Preparations/administration & dosage; Drug Resistance, Neoplasm; Female; Humans; Leukocytes, Mononuclear/metabolism; Liver Neoplasms/metabolism; Male; Niacinamide/analogs & derivatives; Nitric Oxide/blood; Octreotide/administration & dosage; Phenylurea Compounds; Phosphorylation; Pyridines/administration & dosage; Reactive Oxygen Species/blood; Sorafenib; Superoxide Dismutase/blood; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Biomarkers, Tumor / Carcinoma, Hepatocellular / Oxidative Stress / Mitogen-Activated Protein Kinase 1 / Mitogen-Activated Protein Kinase 3 / Liver Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Cell Death Dis Year: 2011 Document type: Article

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