A 5-year prospective follow-up study in essential cryofibrinogenemia patients.
Autoimmun Rev
; 10(9): 559-62, 2011 Jul.
Article
in En
| MEDLINE
| ID: mdl-21549859
ABSTRACT
INTRODUCTION:
Cryofibrinogenemia may be essential, or secondary to diseases such as neoplasia, infection, thrombosis, and collagen vascular diseases. In a previous study, we reported the occurrence of neoplasia in some essential cryofibrinogenemia patients after a short period of follow-up.PURPOSE:
We performed a prospective multi-center 5-year follow-up study in essential cryofibrinogenemia patients (2005-2009).RESULTS:
23 patients with essential cryofibrinogenemia were included, mean age 59 years (range 33-79), 14 males. After a mean follow-up period of 24 months, 11/23 (47%) of cases that were initially diagnosed as essential cryofibrinogenemia were found to have an underlying lymphoma (6 T lymphoma and 5 B lymphoma).CONCLUSION:
This prospective study suggests that some cases of cryofibrinogenemia that are initially considered as essential, may have underlying lymphoma. Thus, we further suggest that regular follow-up should be performed in patients with essential cryofibrinogenemia.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cryoglobulinemia
/
Lymphoma
Type of study:
Clinical_trials
/
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Autoimmun Rev
Year:
2011
Document type:
Article