p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia.

Ng, K P; Ebrahem, Q; Negrotto, S; Mahfouz, R Z; Link, K A; Hu, Z; Gu, X; Advani, A; Kalaycio, M; Sobecks, R; Sekeres, M; Copelan, E; Radivoyevitch, T; Maciejewski, J; Mulloy, J C; Saunthararajah, Y

Ng, K P; Ebrahem, Q; Negrotto, S; Mahfouz, R Z; Link, K A; Hu, Z; Gu, X; Advani, A; Kalaycio, M; Sobecks, R; Sekeres, M; Copelan, E; Radivoyevitch, T; Maciejewski, J; Mulloy, J C; Saunthararajah, Y.

Affiliation

Ng KP; Department of Translational Hematology & Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

Leukemia ; 25(11): 1739-50, 2011 Nov.

Article in En | MEDLINE | ID: mdl-21701495

Subject(s)

Epigenesis, Genetic; Genes, p53; Leukemia, Myeloid, Acute/drug therapy; Transplantation, Heterologous; Animals; Antineoplastic Agents/therapeutic use; Apoptosis; Azacitidine/analogs & derivatives; Azacitidine/therapeutic use; Blotting, Western; Cell Differentiation; Cytarabine/therapeutic use; DNA Damage; Decitabine; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid, Acute/genetics; Leukemia, Myeloid, Acute/pathology; Mice; Phosphorylation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transplantation, Heterologous / Leukemia, Myeloid, Acute / Genes, p53 / Epigenesis, Genetic Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Leukemia Year: 2011 Document type: Article

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