Interactions between gastric and enteric infections: clues to the pathogenesis of inflammatory bowel disease?
N Z Med J
; 124(1332): 62-7, 2011 Apr 15.
Article
in En
| MEDLINE
| ID: mdl-21747425
Whereas the worldwide incidence of Crohn's disease (CD) continues to rise, Maori and Pacific Islanders living in New Zealand remain largely unaffected. The reason for this is currently unknown but may be linked to emerging evidence suggesting a role for Campylobacter spp in the aetiology of CD. Rates of campylobacteriosis are notably lower among Maori and Pacific Islanders and while this may reflect poorer access to primary care and diagnostic services, resulting in lower rates of notified disease, we consider it may also reflect a level of protective immunity in Maori and Pacific Islanders as a result of chronic infection from an early age with the closely related gastric pathogen Helicobacter pylori. Understanding the interactions between these antigenically-related bacteria may provide us with clues that ultimately help unravel the complex aetiology of CD.
Search on Google
Collection:
01-internacional
Health context:
11_ODS3_cobertura_universal
/
3_ND
Database:
MEDLINE
Main subject:
Campylobacter
/
Campylobacter Infections
/
Crohn Disease
/
Helicobacter pylori
/
Helicobacter Infections
/
Enteritis
/
Gastritis
Type of study:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
/
Screening_studies
Limits:
Adult
/
Child
/
Female
/
Humans
/
Male
Country/Region as subject:
Oceania
Language:
En
Journal:
N Z Med J
Year:
2011
Document type:
Article