Long-term treatment with ivabradine in post-myocardial infarcted rats counteracts f-channel overexpression.

Suffredini, S; Stillitano, F; Comini, L; Bouly, M; Brogioni, S; Ceconi, C; Ferrari, R; Mugelli, A; Cerbai, E

Suffredini, S; Stillitano, F; Comini, L; Bouly, M; Brogioni, S; Ceconi, C; Ferrari, R; Mugelli, A; Cerbai, E.

Affiliation

Suffredini S; Center of Molecular Medicine (C.I.M.M.B.A.), Florence, Italy.

Br J Pharmacol ; 165(5): 1457-66, 2012 Mar.

Article in En | MEDLINE | ID: mdl-21838751

Subject(s)

Benzazepines/pharmacology; Myocardial Infarction/drug therapy; Myocardial Infarction/metabolism; Myocytes, Cardiac/drug effects; Myocytes, Cardiac/metabolism; Animals; Cyclic Nucleotide-Gated Cation Channels/genetics; Cyclic Nucleotide-Gated Cation Channels/metabolism; Heart Atria/drug effects; Heart Atria/metabolism; Heart Rate/drug effects; Heart Rate/genetics; Heart Ventricles/drug effects; Heart Ventricles/metabolism; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels/genetics; Ion Channels/metabolism; Ivabradine; Male; MicroRNAs/genetics; MicroRNAs/metabolism; Potassium Channels/genetics; Potassium Channels/metabolism; Rats; Rats, Wistar; Ventricular Remodeling/drug effects; Ventricular Remodeling/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzazepines / Myocytes, Cardiac / Myocardial Infarction Limits: Animals Language: En Journal: Br J Pharmacol Year: 2012 Document type: Article

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