Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand.

Jain, Ashish; Kovacs, Joseph A; Nelson, David L; Migueles, Stephen A; Pittaluga, Stefania; Fanslow, William; Fan, Xiying; Wong, Duane W; Massey, Justin; Hornung, Ronald; Brown, Margaret R; Spinner, Jacob J; Liu, Shuying; Davey, Victoria; Hill, Harry A; Ochs, Hans; Fleisher, Thomas A

Jain, Ashish; Kovacs, Joseph A; Nelson, David L; Migueles, Stephen A; Pittaluga, Stefania; Fanslow, William; Fan, Xiying; Wong, Duane W; Massey, Justin; Hornung, Ronald; Brown, Margaret R; Spinner, Jacob J; Liu, Shuying; Davey, Victoria; Hill, Harry A; Ochs, Hans; Fleisher, Thomas A.

Affiliation

Jain A; Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA. ajain@nih.gov

Blood ; 118(14): 3811-7, 2011 Oct 06.

Article in En | MEDLINE | ID: mdl-21841160

Subject(s)

CD40 Ligand/therapeutic use; Hyper-IgM Immunodeficiency Syndrome, Type 1/immunology; Hyper-IgM Immunodeficiency Syndrome, Type 1/therapy; Recombinant Proteins/therapeutic use; Adolescent; Animals; CD40 Ligand/administration & dosage; CD40 Ligand/adverse effects; CD40 Ligand/immunology; Child; Follow-Up Studies; Humans; Hyper-IgM Immunodeficiency Syndrome, Type 1/pathology; Immunotherapy; Interferon-gamma/immunology; Lymph Nodes/drug effects; Lymph Nodes/immunology; Lymph Nodes/pathology; Mice; Recombinant Proteins/administration & dosage; Recombinant Proteins/adverse effects; Recombinant Proteins/immunology; T-Lymphocytes/drug effects; T-Lymphocytes/immunology; T-Lymphocytes/pathology; Tumor Necrosis Factor-alpha/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / CD40 Ligand / Hyper-IgM Immunodeficiency Syndrome, Type 1 Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Animals / Child / Humans Language: En Journal: Blood Year: 2011 Document type: Article

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