[Hypophosphatemia and tumor-induced osteomalacia]. / Hypophosphatémie et ostéomalacie oncogénique.
Rev Med Suisse
; 7(306): 1630-3, 2011 Aug 31.
Article
in Fr
| MEDLINE
| ID: mdl-21972729
ABSTRACT
In this article, we will discuss about hypophosphatemia due to tumor-induced osteomalacia. This disease is characterized by severe muscular and articular tenderness inducing profound walking limitation. Clinical chemistry results show severe hypophosphatemia due to hyperphosphaturia. Fibroblast growth factor 23 (FGF-23) is abnormally high. Physiological role of FGF-23 is examined. We also consider the pathophysiology of tumor induced osteomalacia, the use of different investigations to localize the tumor and therapies available to treat this rare disease.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Osteomalacia
/
Hypophosphatemia
/
Neoplasms
Type of study:
Etiology_studies
Limits:
Humans
Language:
Fr
Journal:
Rev Med Suisse
Year:
2011
Document type:
Article