A threat of the Klebsiella pneumoniae carbapenemase-producing strains among transplant recipients.
Transplant Proc
; 43(8): 3135-6, 2011 Oct.
Article
in En
| MEDLINE
| ID: mdl-21996247
ABSTRACT
BACKGROUND:
Infections due to Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae are associated with increased therapeutic failure and mortality. Our laboratory recognized several strains producing KPC, most of which originated from transplantation ward patients. MATERIALS ANDMETHODS:
All strains of K pneumoniae resistant to at least 1 carbapenem isolated in 2010 were examined for KPC production by disc diffusion and then verified by molecular methods.RESULTS:
All positive strains originated from 7 patients. Six of them were from transplantation wards. None of the KPC-producing strains was isolated from the patient's blood.CONCLUSIONS:
A quick, accurate diagnosis of KPC-producing strains enabled immediate isolation of carriers or infected persons. Isolation prevented spread of dangerous strains among immunocompromised patients and reduced the possibility of serious infections.
Full text:
1
Collection:
01-internacional
Health context:
3_ND
Database:
MEDLINE
Main subject:
Bacterial Proteins
/
Beta-Lactamases
/
Klebsiella Infections
/
Kidney Transplantation
/
Liver Transplantation
/
Klebsiella pneumoniae
Type of study:
Etiology_studies
Limits:
Humans
Language:
En
Journal:
Transplant Proc
Year:
2011
Document type:
Article