The validation of matrix metalloproteinase-9 mRNA gene expression as a predictor of outcome in patients with metastatic gastric cancer.

Al-Batran, S-E; Pauligk, C; Wirtz, R; Werner, D; Steinmetz, K; Homann, N; Schmalenberg, H; Hofheinz, R-D; Hartmann, J T; Atmaca, A; Altmannsberger, H-M; Jäger, E

Al-Batran, S-E; Pauligk, C; Wirtz, R; Werner, D; Steinmetz, K; Homann, N; Schmalenberg, H; Hofheinz, R-D; Hartmann, J T; Atmaca, A; Altmannsberger, H-M; Jäger, E.

Affiliation

Al-Batran SE; Department of Hematology and Oncology, Institute of clinical research (IKF) at Krankenhaus Nordwest, UCT-University Cancer Center, Frankfurt am Main, Germany. albatran@aol.com

Ann Oncol ; 23(7): 1699-705, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22112973

Subject(s)

Adenocarcinoma/enzymology; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Gene Expression; Matrix Metalloproteinase 9/genetics; Stomach Neoplasms/enzymology; Adenocarcinoma/drug therapy; Adenocarcinoma/mortality; Adenocarcinoma/secondary; Adult; Aged; Aged, 80 and over; Cisplatin/administration & dosage; Clinical Trials, Phase III as Topic; Docetaxel; ErbB Receptors/genetics; ErbB Receptors/metabolism; Female; Fluorouracil/administration & dosage; Humans; Kaplan-Meier Estimate; Leucovorin/administration & dosage; Male; Matrix Metalloproteinase 9/metabolism; Middle Aged; Multivariate Analysis; Organoplatinum Compounds/administration & dosage; Oxaliplatin; Prognosis; Proportional Hazards Models; Stomach Neoplasms/drug therapy; Stomach Neoplasms/mortality; Stomach Neoplasms/pathology; Taxoids/administration & dosage; Treatment Outcome; Vascular Endothelial Growth Factor A/genetics; Vascular Endothelial Growth Factor A/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Adenocarcinoma / Antineoplastic Combined Chemotherapy Protocols / Gene Expression / Matrix Metalloproteinase 9 Type of study: Prognostic_studies / Risk_factors_studies Limits: Aged80 Language: En Journal: Ann Oncol Year: 2012 Document type: Article

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