Synthesis and antihormonal properties of novel 11ß-benzoxazole-substituted steroids.

Jin, Chunyang; Fix, Scott E; Kepler, John A; Cook, C Edgar

Jin, Chunyang; Fix, Scott E; Kepler, John A; Cook, C Edgar.

Affiliation

Jin C; Center for Organic and Medicinal Chemistry, Research Triangle Institute, Research Triangle Park, NC 27709-2194, USA. cjin@rti.org

Bioorg Med Chem Lett ; 22(4): 1705-8, 2012 Feb 15.

Article in En | MEDLINE | ID: mdl-22260770

Subject(s)

Hormone Antagonists/chemical synthesis; Hormone Antagonists/pharmacology; Receptors, Glucocorticoid/antagonists & inhibitors; Receptors, Progesterone/antagonists & inhibitors; Steroids/chemical synthesis; Steroids/pharmacology; Benzoxazoles/chemical synthesis; Benzoxazoles/chemistry; Benzoxazoles/pharmacology; Cell Line, Tumor; Hormone Antagonists/chemistry; Humans; Inhibitory Concentration 50; Mifepristone/chemistry; Molecular Structure; Steroids/chemistry; Substrate Specificity/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Steroids / Receptors, Glucocorticoid / Receptors, Progesterone / Hormone Antagonists Limits: Humans Language: En Journal: Bioorg Med Chem Lett Year: 2012 Document type: Article

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