Sgp3 and TLR7 stimulation differentially alter the expression profile of modified polytropic retroviruses implicated in murine systemic lupus.

Leroy, Valérie; Kihara, Masao; Baudino, Lucie; Brighouse, Guy; Evans, Leonard H; Izui, Shozo

Leroy, Valérie; Kihara, Masao; Baudino, Lucie; Brighouse, Guy; Evans, Leonard H; Izui, Shozo.

Affiliation

Leroy V; Department of Pathology and Immunology, University of Geneva, 1211 Geneva 4, Switzerland.

J Autoimmun ; 38(4): 361-8, 2012 Jun.

Article in En | MEDLINE | ID: mdl-22503566

Subject(s)

Endogenous Retroviruses/drug effects; Endogenous Retroviruses/genetics; Glycoproteins/metabolism; Lupus Erythematosus, Systemic/genetics; Molecular Chaperones/metabolism; Toll-Like Receptor 7/agonists; Adenine/analogs & derivatives; Adenine/pharmacology; Animals; DNA Replication; Female; Gene Expression Regulation/drug effects; Genome; Glycoproteins/genetics; Liver/metabolism; Lupus Erythematosus, Systemic/immunology; Mice; Mice, Inbred C57BL; Mice, Inbred NZB; Molecular Chaperones/genetics; Proviruses/genetics; Thymus Gland/metabolism; Transcription, Genetic/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycoproteins / Molecular Chaperones / Endogenous Retroviruses / Toll-Like Receptor 7 / Lupus Erythematosus, Systemic Limits: Animals Language: En Journal: J Autoimmun Year: 2012 Document type: Article

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