Mutation profiling identifies numerous rare drug targets and distinct mutation patterns in different clinical subtypes of breast cancers.

Santarpia, Libero; Qi, Yuan; Stemke-Hale, Katherine; Wang, Bailiang; Young, Elliana J; Booser, Daniel J; Holmes, Frankie A; O'Shaughnessy, Joyce; Hellerstedt, Beth; Pippen, John; Vidaurre, Tatiana; Gomez, Henry; Valero, Vicente; Hortobagyi, Gabriel N; Symmans, W Fraser; Bottai, Giulia; Di Leo, Angelo; Gonzalez-Angulo, Ana M; Pusztai, Lajos

Santarpia, Libero; Qi, Yuan; Stemke-Hale, Katherine; Wang, Bailiang; Young, Elliana J; Booser, Daniel J; Holmes, Frankie A; O'Shaughnessy, Joyce; Hellerstedt, Beth; Pippen, John; Vidaurre, Tatiana; Gomez, Henry; Valero, Vicente; Hortobagyi, Gabriel N; Symmans, W Fraser; Bottai, Giulia; Di Leo, Angelo; Gonzalez-Angulo, Ana M; Pusztai, Lajos.

Affiliation

Santarpia L; Department of Oncology, Translational Research Unit, Hospital of Prato and Istituto Toscano Tumori, 59100, Prato, Italy. lsantarpia@usl4.toscana.it

Breast Cancer Res Treat ; 134(1): 333-43, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22538770

Subject(s)

Breast Neoplasms/genetics; Mutation; Breast Neoplasms/drug therapy; Breast Neoplasms/metabolism; DNA Mutational Analysis; Female; Genes; Genetic Association Studies; Humans; Molecular Targeted Therapy; Multivariate Analysis; Polymorphism, Single Nucleotide; Receptor, ErbB-2/metabolism; Receptors, Estrogen/metabolism; Receptors, Progesterone/metabolism; Signal Transduction/genetics

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Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 Database: MEDLINE Main subject: Breast Neoplasms / Mutation Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Breast Cancer Res Treat Year: 2012 Document type: Article

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