MicroRNA-21 expression is regulated by ß-catenin/STAT3 pathway and promotes glioma cell invasion by direct targeting RECK.

Han, Lei; Yue, Xiao; Zhou, Xuan; Lan, Feng-Ming; You, Gan; Zhang, Wei; Zhang, Kai-Liang; Zhang, Chun-Zhi; Cheng, Jin-Quan; Yu, Shi-Zhu; Pu, Pei-Yu; Jiang, Tao; Kang, Chun-Sheng

Han, Lei; Yue, Xiao; Zhou, Xuan; Lan, Feng-Ming; You, Gan; Zhang, Wei; Zhang, Kai-Liang; Zhang, Chun-Zhi; Cheng, Jin-Quan; Yu, Shi-Zhu; Pu, Pei-Yu; Jiang, Tao; Kang, Chun-Sheng.

Affiliation

Han L; Department of Neurosurgery, Tianjin Medical University General Hospital, China.

CNS Neurosci Ther ; 18(7): 573-83, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22630347

Subject(s)

GPI-Linked Proteins/metabolism; Gene Expression Regulation, Neoplastic; Glioma/metabolism; MicroRNAs/metabolism; STAT3 Transcription Factor/physiology; beta Catenin/physiology; Animals; Cell Line, Tumor; Down-Regulation/genetics; GPI-Linked Proteins/genetics; Gene Knockdown Techniques/methods; Gene Targeting/methods; Glioma/genetics; Glioma/pathology; Humans; Mice; Mice, Nude; MicroRNAs/biosynthesis; Neoplasm Invasiveness/genetics; Neoplasm Invasiveness/pathology; Umbilical Veins/cytology; Umbilical Veins/metabolism; Up-Regulation/genetics; Xenograft Model Antitumor Assays/methods

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / MicroRNAs / STAT3 Transcription Factor / Beta Catenin / GPI-Linked Proteins / Glioma Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: CNS Neurosci Ther Year: 2012 Document type: Article

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