An affective disorder in zebrafish with mutation of the glucocorticoid receptor.

Ziv, L; Muto, A; Schoonheim, P J; Meijsing, S H; Strasser, D; Ingraham, H A; Schaaf, M J M; Yamamoto, K R; Baier, H

Ziv, L; Muto, A; Schoonheim, P J; Meijsing, S H; Strasser, D; Ingraham, H A; Schaaf, M J M; Yamamoto, K R; Baier, H.

Affiliation

Ziv L; Department of Physiology, Programs in Neuroscience, Genetics, and Developmental and Stem Cell Biology, University of California, San Francisco, CA, USA.

Mol Psychiatry ; 18(6): 681-91, 2013 Jun.

Article in En | MEDLINE | ID: mdl-22641177

Subject(s)

Mood Disorders/genetics; Mutation/genetics; Receptors, Glucocorticoid/genetics; Analysis of Variance; Animals; Animals, Genetically Modified; Anti-Anxiety Agents/pharmacology; Anti-Anxiety Agents/therapeutic use; Arginine/genetics; Brain/metabolism; Cell Line, Transformed; Chlorocebus aethiops; Corticotropin-Releasing Hormone/genetics; Corticotropin-Releasing Hormone/metabolism; Cysteine/genetics; Diazepam/pharmacology; Diazepam/therapeutic use; Disease Models, Animal; Escape Reaction/drug effects; Escape Reaction/physiology; Exploratory Behavior/drug effects; Exploratory Behavior/physiology; Fluoxetine/pharmacology; Fluoxetine/therapeutic use; Freezing Reaction, Cataleptic/physiology; Hormone Antagonists/pharmacology; Humans; Hydrocortisone/blood; Interpersonal Relations; Mifepristone/pharmacology; Mood Disorders/diet therapy; Mood Disorders/metabolism; Mood Disorders/pathology; Psychomotor Agitation/genetics; Psychomotor Agitation/pathology; Radioimmunoassay; Receptors, Glucocorticoid/metabolism; Serotonin/genetics; Serotonin/metabolism; Transfection; Zebrafish

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Glucocorticoid / Mood Disorders / Mutation Type of study: Prognostic_studies Language: En Journal: Mol Psychiatry Year: 2013 Document type: Article

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