Dissecting pharmacodynamics to determine the optimal sampling time and measurement for assessing the antiplatelet effect of clopidogrel.

Kim, S-D; Jeong, Y-H; Lee, S-W; Shin, I H; Park, J-Y; Park, S-W; Yoon, Y-R; Song, J-K

Kim, S-D; Jeong, Y-H; Lee, S-W; Shin, I H; Park, J-Y; Park, S-W; Yoon, Y-R; Song, J-K.

J Thromb Haemost ; 10(10): 2196-9, 2012 Oct.

Article in En | MEDLINE | ID: mdl-22845896

Subject(s)

Drug Monitoring/methods; Platelet Aggregation Inhibitors/administration & dosage; Platelet Aggregation/drug effects; Platelet Function Tests; Ticlopidine/analogs & derivatives; Adult; Area Under Curve; Clopidogrel; Humans; Linear Models; Male; Middle Aged; Models, Biological; Platelet Aggregation Inhibitors/pharmacokinetics; Predictive Value of Tests; Reproducibility of Results; Retrospective Studies; Ticlopidine/administration & dosage; Ticlopidine/pharmacokinetics; Treatment Outcome; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Platelet Function Tests / Ticlopidine / Platelet Aggregation Inhibitors / Platelet Aggregation / Drug Monitoring Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Humans / Male / Middle aged Language: En Journal: J Thromb Haemost Year: 2012 Document type: Article

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