Crystal structure and functional analysis of JMJD5 indicate an alternate specificity and function.

Del Rizzo, Paul A; Krishnan, Swathi; Trievel, Raymond C

Del Rizzo, Paul A; Krishnan, Swathi; Trievel, Raymond C.

Affiliation

Del Rizzo PA; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA.

Mol Cell Biol ; 32(19): 4044-52, 2012 Oct.

Article in En | MEDLINE | ID: mdl-22851697

Subject(s)

Amino Acids, Dicarboxylic/metabolism; Histone Demethylases/chemistry; Histone Demethylases/metabolism; Ketoglutaric Acids/metabolism; Catalytic Domain; Crystallography, X-Ray; Histone Demethylases/antagonists & inhibitors; Histone Demethylases/genetics; Humans; Jumonji Domain-Containing Histone Demethylases/chemistry; Jumonji Domain-Containing Histone Demethylases/genetics; Jumonji Domain-Containing Histone Demethylases/metabolism; Models, Molecular; Phylogeny; Protein Conformation; Structural Homology, Protein; Substrate Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histone Demethylases / Amino Acids, Dicarboxylic / Ketoglutaric Acids Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Biol Year: 2012 Document type: Article

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