3-D simulation of nanopore structure for DNA sequencing.
J Nanosci Nanotechnol
; 12(7): 5160-3, 2012 Jul.
Article
in En
| MEDLINE
| ID: mdl-22966538
ABSTRACT
In this paper, we propose a method for simulating nanopore structure by using conventional 3-D simulation tool to mimic the I-V behavior of the nanopore structure. In the simulation, we use lightly doped silicon for ionic solution where some parameters like electron affinity and dielectric constant are fitted to consider the ionic solution. By using this method, we can simulate the I-V behavior of nanopore structure depending on the location and the size of the sphere shaped silicon oxide which is considered to be an indicator of a DNA base. In addition, we simulate an Ionic Field Effect Transistor (IFET) which has basically the nanopore structure, and show that the simulated curves follow sufficiently the I-V behavior of the measurement data. Therefore, we think it is reasonable to apply parameter modeling mentioned above to simulate nanopore structure. The key idea is to modify electron affinity of silicon which is used to mimic the KCl solution to avoid band bending and depletion inside the nanopore. We could efficiently utilize conventional 3-D simulation tool to simulate the I-V behavior of nanopore structures.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
DNA
/
Sequence Analysis, DNA
/
Computer-Aided Design
/
Conductometry
/
Nanotechnology
/
Nanostructures
Language:
En
Journal:
J Nanosci Nanotechnol
Year:
2012
Document type:
Article