Immunoglobulin g from breast cancer patients regulates MCF-7 cells migration and MMP-9 activity by stimulating muscarinic acetylcholine receptors.

Pelegrina, Laura T; Lombardi, María Gabriela; Fiszman, Gabriel L; Azar, María E; Morgado, Carlos Cresta; Sales, María E

Pelegrina, Laura T; Lombardi, María Gabriela; Fiszman, Gabriel L; Azar, María E; Morgado, Carlos Cresta; Sales, María E.

Affiliation

Pelegrina LT; Centro de Estudios Farmacológicos y Botánicos (CEFYBO)-CONICET, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155 piso 16, Buenos Aires, CP 1121, Argentina.

J Clin Immunol ; 33(2): 427-35, 2013 Feb.

Article in En | MEDLINE | ID: mdl-23007238

Subject(s)

Autoantibodies/immunology; Breast Neoplasms/immunology; Breast Neoplasms/metabolism; Cell Movement; Immunoglobulin G/immunology; Matrix Metalloproteinase 9/metabolism; Receptors, Muscarinic/immunology; Autoantibodies/pharmacology; Carbachol/pharmacology; Cell Movement/drug effects; Cholinergic Agonists/pharmacology; Enzyme Activation/drug effects; Female; Humans; Immunoglobulin G/pharmacology; MCF-7 Cells; Nitric Oxide Synthase/metabolism; Phosphoinositide Phospholipase C/metabolism; Protein Kinase C/metabolism; Receptors, Muscarinic/metabolism; Signal Transduction

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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Autoantibodies / Breast Neoplasms / Immunoglobulin G / Cell Movement / Receptors, Muscarinic / Matrix Metalloproteinase 9 Limits: Female / Humans Language: En Journal: J Clin Immunol Year: 2013 Document type: Article

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