Huperzia quadrifariata and Huperzia reflexa alkaloids inhibit acetylcholinesterase activity in vivo in mice brain.

Konrath, E L; Neves, B M; Passos, C Dos S; Lunardi, P S; Ortega, M G; Cabrera, J L; Gonçalves, C A; Henriques, A T

Konrath, E L; Neves, B M; Passos, C Dos S; Lunardi, P S; Ortega, M G; Cabrera, J L; Gonçalves, C A; Henriques, A T.

Affiliation

Konrath EL; Programa de Pós Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. edukonrath@yahoo.com.br

Phytomedicine ; 19(14): 1321-4, 2012 Nov 15.

Article in En | MEDLINE | ID: mdl-23022390

Subject(s)

Acetylcholinesterase/metabolism; Alkaloids/pharmacology; Alzheimer Disease/metabolism; Brain/drug effects; Cholinesterase Inhibitors/pharmacology; Huperzia/chemistry; Plant Extracts/pharmacology; Alkaloids/therapeutic use; Alzheimer Disease/drug therapy; Animals; Brain/metabolism; Cerebral Cortex/drug effects; Cholinesterase Inhibitors/therapeutic use; Hippocampus/drug effects; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Phytotherapy; Plant Extracts/therapeutic use; Sesquiterpenes/pharmacology; Sesquiterpenes/therapeutic use

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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Acetylcholinesterase / Brain / Plant Extracts / Cholinesterase Inhibitors / Huperzia / Alkaloids / Alzheimer Disease Limits: Animals Language: En Journal: Phytomedicine Year: 2012 Document type: Article

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