Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data.

Doktorova, Tatyana Y; Ellinger-Ziegelbauer, Heidrun; Vinken, Mathieu; Vanhaecke, Tamara; van Delft, Joost; Kleinjans, Jos; Ahr, Hans-Juergen; Rogiers, Vera

Doktorova, Tatyana Y; Ellinger-Ziegelbauer, Heidrun; Vinken, Mathieu; Vanhaecke, Tamara; van Delft, Joost; Kleinjans, Jos; Ahr, Hans-Juergen; Rogiers, Vera.

Affiliation

Doktorova TY; Department of Toxicology, Center for Pharmaceutical Research (CePhar), Vrije Universiteit Brussel (VUB), Laarbeeklaan 103, Brussels, Belgium. tatyana.yordanova.doktorova@vub.ac.be

Arch Toxicol ; 86(11): 1703-15, 2012 Nov.

Article in En | MEDLINE | ID: mdl-23052194

Subject(s)

Gene Expression Profiling; Hepatocytes/drug effects; Mutagens/toxicity; Toxicogenetics/methods; Aflatoxin B1/toxicity; Animals; Carcinogens/toxicity; Cells, Cultured; DNA Damage/drug effects; Epigenesis, Genetic; Fluorenes/toxicity; Hepatocytes/physiology; Male; Mutagenicity Tests; Nitrosamines/toxicity; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Profiling / Hepatocytes / Toxicogenetics / Mutagens Limits: Animals Language: En Journal: Arch Toxicol Year: 2012 Document type: Article

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