Synovial cell sarcoma of the larynx.
Hematol Oncol Clin North Am
; 26(6): 1209-19, 2012 Dec.
Article
in En
| MEDLINE
| ID: mdl-23116577
ABSTRACT
Synovial cell sarcoma represents a rare group of cancers, particularly in the head and neck region, that typically affects young individuals and has a male preponderance. Prognosis varies with patient age, site and size of the malignancy, degree of necrosis, high level of mitotic activity, and neurovascular invasion. Complete surgical resection of the tumor via partial or total laryngectomy is the first-line treatment in locally invasive disease. CO(2) lasers have been shown to be useful in controlling localized disease. There is also a role for adjuvant radiotherapy. Ifosfamide-based chemotherapy is most useful for malignant disease.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Laryngeal Neoplasms
/
Sarcoma, Synovial
Type of study:
Etiology_studies
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Hematol Oncol Clin North Am
Year:
2012
Document type:
Article